Searchable abstracts of presentations at key conferences in endocrinology

ea0014p546 | (1) | ECE2007

ACTH and cortisol responses to ghrelin and DDAVP in patients with Cushing’s disease (CD)

Miljic Dragana , Doknic Mirjana , Pekic Sandra , Djurovic Marina , Penezic Zorana , Damjanovic Svetozar , Macut Djuro , Sumarac-Dumanovic Mirjana , Popovic Bojana , Ghatei Mohammad , Popovic Vera

Aim of this study was to investigate head to head ACTH and cortisol responses to DDAVP and ghrelin in patients with CD. Study was approved by the local ethics committee and informed consent obtained. Nine patients with CD were submitted to ghrelin 1 μg/kg and DDAVP 10 μg bolus iv administration on two separate occasions. Blood was sampled at 0.15, 30, 45, 60, 90 min. for ACTH (ELISA) and cortisol (RIA, Cis, Bio International, France) measurements.<p class="abstex...